Poker, believe it or not, is a game of odds. Get in when you have the best odds. Get out, when you don't (or bluff). You can have a boat cracked by quads, and quads cracked by a straight flush. If you play too scared to make a move with the best hand - you'll never win at this game.
And whoever said "taking the chip lead early in a large tournament means nothing" is plain wrong. Survival is number one, granted, but survival becomes very easy when you triple up on the first hand.
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