This happens a lot to me at my home games as the host and I are usually the last ones there. We play heads up for a while, usually just giving money back and forth. In these situations I always bet on AA or KK and bet big. Partly because I know my opponent but also there is something about loosing with AA or KK in the hole......it just doesn't feel right. I would rather take the blinds then be the victim of a bad beat. I'll make my money with something else or when the table isn't short handed.